{"id":1626,"date":"2021-10-26T09:59:26","date_gmt":"2021-10-26T07:59:26","guid":{"rendered":"https:\/\/www.septabene.si\/?p=1626"},"modified":"2021-11-26T10:53:16","modified_gmt":"2021-11-26T09:53:16","slug":"novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo","status":"publish","type":"post","link":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/","title":{"rendered":"Novi dokazi o protivirusnem delovanju pastil za grlo"},"content":{"rendered":"        <div >\r\n            \n\n<p>Nova <em>in&nbsp;vitro<\/em> \u0161tudija o pastilah, ki vsebujejo fiksno kombinacijo benzidaminijevega klorida (benzidamin, BK) in cetilpiridinijevega klorida (cetilpiridinij, CPK), je <strong>potrdila njihovo protivirusno delovanje proti SARS-CoV-2<\/strong>. Ovojnica virusa SARS-CoV-2 je bila v razmerah, ki so podobne fiziolo\u0161kemu okolju v ustni votlini, po izpostavljenosti pastili uni\u010dena. Rezultati ka\u017eejo, da je bilo <strong>ve\u010d kot 99,99&nbsp;% SARS-CoV-2 uni\u010denega \u017ee v prvih minutah delovanja<\/strong>. (1)<\/p>\n\n\n        <img class=\"illnes \" src=\"\/wp-content\/uploads\/raziskava-sars-cov-2.jpg\">\r\n\t\t\n        <\/div>\r\n\t\t\n\n        <div >\r\n            \n\n<h5><strong><strong> <strong>SARS-CoV-2 in vneto grlo<\/strong> <\/strong><\/strong><\/h5>\n\n\n\n<p>Vneto grlo najpogosteje povzro\u010dajo virusi \u2013 <strong>do 95&nbsp;% primerov pri odraslih<\/strong> in <strong>do 70&nbsp;% primerov pri otrocih<\/strong>. Med ostalimi vzroki so bakterije, glivice in drugi dejavniki (npr. kajenje). (3, 4)<\/p>\n\n\n\n<p>SARS-CoV-2 spada v dru\u017eino koronavirusov in povzro\u010da covid-19. Simptomi te bolezni so lahko blagi do hudi in se od osebe do osebe razlikujejo. Eden od najpogostej\u0161ih je <strong>vneto grlo<\/strong> (2), ki ga spremljajo bole\u010dina in dra\u017eenje v grlu ter zmanj\u0161ana kakovost \u017eivljenja (te\u017eave s po\u017eiranjem sline in teko\u010dine, hripavost, izguba energije itd.).<\/p>\n\n        <\/div>\r\n\t\t\n\n        <div >\r\n            \n\n<h5><strong><strong> <strong>Protivirusno delovanje proti SARS-CoV-2 je potrjeno <em>in&nbsp;vitro<\/em><\/strong> <\/strong><\/strong><\/h5>\n\n\n\n<p>Cetilpiridinijev klorid je u\u010dinkovit proti virusom z ovojnico, bakterijam in glivicam. Ciljno deluje na ovojnico virusa, zaradi \u010desar ta izgubi infektivnost (ku\u017enost). To so potrdili tudi za virus, ki povzro\u010da gripo. (5) V&nbsp;zadnjih dveh letih so opravili nekaj \u0161tudij o vplivu CPK ali podobnih u\u010dinkovin na SARS-CoV-2. \u0160tudija o pastilah, ki vsebujejo BK in CPK, je prva preverila delovanje te edinstvene kombinacije proti SARS-CoV-2. Rezultati ka\u017eejo, da je bilo <strong>ve\u010d<\/strong> <strong>kot 99,99&nbsp;% SARS-CoV-2 uni\u010denega \u017ee v prvih minutah delovanja<\/strong>. <\/p>\n\n\n        <img class=\"illnes \" src=\"\/wp-content\/uploads\/forweb_unicenje-sars-cov2.png\">\r\n\t\t\n\n\n<p><strong>Pri pastilah s kombinacijo benzidaminijevega klorida (BK) in cetilpiridinijevega klorida (CPK) je bilo zmanj\u0161anje koncentracije virusa opazno \u017ee po 1\u00a0minuti delovanja.<\/strong> V primeru u\u010dinkovine CPK, je bilo podobno zmanj\u0161anje mogo\u010de opaziti \u0161ele po 15 minutah. (1) <\/p>\n\n\n\n<h5><strong>Rezultati \u0161tudije so objavljeni v <a href=\"https:\/\/www.mdpi.com\/2673-8112\/1\/2\/37\">mednarodni reviji Covid<\/a>.<\/strong> <\/h5>\n\n        <\/div>\r\n\t\t\n\n        <div class=\" text-link-sources text-link-sources\">\r\n            \n\n<h5>Literatura<\/h5>\n\n\n\n<ol type=\"1\"><li>Steyer A, Maru\u0161i\u0107 M, Kolenc M, Triglav T. A Throat Lozenge with Fixed Combination of Cetylpyridinium Chloride and Benzydamine Hydrochloride Has Direct Virucidal Effect on SARS-CoV-2. COVID. 2021; 1(2):435-446. <a href=\"https:\/\/doi.org\/10.3390\/covid1020037\">https:\/\/doi.org\/10.3390\/covid1020037<\/a><\/li><li><a href=\"https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/healthandsocialcare\/conditionsanddiseases\/articles\/coronaviruscovid19infectionsinthecommunityinengland\/characteristicsofpeopletestingpositiveforcovid19incountriesoftheuk20may2021\">https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/healthandsocialcare\/conditionsanddiseases\/<\/a><br><a href=\"https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/healthandsocialcare\/conditionsanddiseases\/articles\/coronaviruscovid19infectionsinthecommunityinengland\/characteristicsofpeopletestingpositiveforcovid19incountriesoftheuk20may2021\">articles\/coronaviruscovid19infectionsinthecommunityinengland\/characteristicsofpeopletesting<\/a><br><a href=\"https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/healthandsocialcare\/conditionsanddiseases\/articles\/coronaviruscovid19infectionsinthecommunityinengland\/characteristicsofpeopletestingpositiveforcovid19incountriesoftheuk20may2021\">positiveforcovid19incountriesoftheuk20may2021<\/a><\/li><li>Addey D. Incidence, causes, severity and treatment of throat discomfort: a four-region online questionnaire survey. BMC Ear Nose Throat Disord 2012.<\/li><li>Worrall G. Acute sore throat.&nbsp;Can Fam Physician. 2011;57(7):791\u2013794.<\/li><li>Popkin DL, Zilka S, Dimaano M, et al. Cetylpyridinium Chloride (CPC) Exhibits Potent, Rapid Activity Against Influenza Viruses in vitro and in vivo. Pathog Immun. 2017;2(2): 252\u2013269.<\/li><\/ol>\n\n        <\/div>\r\n\t\t","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":1602,"comment_status":"open","ping_status":"open","sticky":false,"template":"single.php","format":"standard","meta":[],"categories":[10],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v17.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Novi dokazi o protivirusnem delovanju pastil za grlo - Septabene<\/title>\n<meta name=\"description\" content=\"Nova in\u00a0vitro \u0161tudija o pastilah s fiksno kombinacijo benzidamina in cetilpiridinijevega klorida je potrdila njihovo protivirusno delovanje proti SARS-CoV-2.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/\" \/>\n<meta property=\"og:locale\" content=\"sl_SI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Novi dokazi o protivirusnem delovanju pastil za grlo - Septabene\" \/>\n<meta property=\"og:description\" content=\"Nova in\u00a0vitro \u0161tudija o pastilah s fiksno kombinacijo benzidamina in cetilpiridinijevega klorida je potrdila njihovo protivirusno delovanje proti SARS-CoV-2.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/\" \/>\n<meta property=\"og:site_name\" content=\"Septabene\" \/>\n<meta property=\"article:published_time\" content=\"2021-10-26T07:59:26+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-11-26T09:53:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.septabene.si\/wp-content\/uploads\/raziskava-sars-cov-2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"853\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"doriscnj\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.septabene.si\/#website\",\"url\":\"https:\/\/www.septabene.si\/\",\"name\":\"Septabene\",\"description\":\"Trojna mo\\u010d, ki hitro uglasi va\\u0161e bole\\u010de grlo.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.septabene.si\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"sl-SI\"},{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#primaryimage\",\"inLanguage\":\"sl-SI\",\"url\":\"\/wp-content\/uploads\/raziskava-sars-cov-2.jpg\",\"contentUrl\":\"\/wp-content\/uploads\/raziskava-sars-cov-2.jpg\",\"width\":1280,\"height\":853,\"caption\":\"in vitro raziskava v laboratoriju\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#webpage\",\"url\":\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/\",\"name\":\"Novi dokazi o protivirusnem delovanju pastil za grlo - Septabene\",\"isPartOf\":{\"@id\":\"https:\/\/www.septabene.si\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#primaryimage\"},\"datePublished\":\"2021-10-26T07:59:26+00:00\",\"dateModified\":\"2021-11-26T09:53:16+00:00\",\"author\":{\"@id\":\"https:\/\/www.septabene.si\/#\/schema\/person\/65ad2ca435785c4e4235f5a245adfc98\"},\"description\":\"Nova in\\u00a0vitro \\u0161tudija o pastilah s fiksno kombinacijo benzidamina in cetilpiridinijevega klorida je potrdila njihovo protivirusno delovanje proti SARS-CoV-2.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#breadcrumb\"},\"inLanguage\":\"sl-SI\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Domov\",\"item\":\"https:\/\/www.septabene.si\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Koristno\",\"item\":\"https:\/\/www.septabene.si\/koristno\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Bolezni\",\"item\":\"https:\/\/www.septabene.si\/koristno\/bolezni\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Novi dokazi o protivirusnem delovanju pastil za grlo\"}]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.septabene.si\/#\/schema\/person\/65ad2ca435785c4e4235f5a245adfc98\",\"name\":\"doriscnj\",\"image\":{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/www.septabene.si\/#personlogo\",\"inLanguage\":\"sl-SI\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/dc6aa88475708565cd14d855a73ba2b5?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/dc6aa88475708565cd14d855a73ba2b5?s=96&d=mm&r=g\",\"caption\":\"doriscnj\"},\"url\":\"https:\/\/www.septabene.si\/author\/doriscnj\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Novi dokazi o protivirusnem delovanju pastil za grlo - Septabene","description":"Nova in\u00a0vitro \u0161tudija o pastilah s fiksno kombinacijo benzidamina in cetilpiridinijevega klorida je potrdila njihovo protivirusno delovanje proti SARS-CoV-2.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/","og_locale":"sl_SI","og_type":"article","og_title":"Novi dokazi o protivirusnem delovanju pastil za grlo - Septabene","og_description":"Nova in\u00a0vitro \u0161tudija o pastilah s fiksno kombinacijo benzidamina in cetilpiridinijevega klorida je potrdila njihovo protivirusno delovanje proti SARS-CoV-2.","og_url":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/","og_site_name":"Septabene","article_published_time":"2021-10-26T07:59:26+00:00","article_modified_time":"2021-11-26T09:53:16+00:00","og_image":[{"width":1280,"height":853,"url":"https:\/\/www.septabene.si\/wp-content\/uploads\/raziskava-sars-cov-2.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Written by":"doriscnj","Est. reading time":"2 minuti"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebSite","@id":"https:\/\/www.septabene.si\/#website","url":"https:\/\/www.septabene.si\/","name":"Septabene","description":"Trojna mo\u010d, ki hitro uglasi va\u0161e bole\u010de grlo.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.septabene.si\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"sl-SI"},{"@type":"ImageObject","@id":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#primaryimage","inLanguage":"sl-SI","url":"\/wp-content\/uploads\/raziskava-sars-cov-2.jpg","contentUrl":"\/wp-content\/uploads\/raziskava-sars-cov-2.jpg","width":1280,"height":853,"caption":"in vitro raziskava v laboratoriju"},{"@type":"WebPage","@id":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#webpage","url":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/","name":"Novi dokazi o protivirusnem delovanju pastil za grlo - Septabene","isPartOf":{"@id":"https:\/\/www.septabene.si\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#primaryimage"},"datePublished":"2021-10-26T07:59:26+00:00","dateModified":"2021-11-26T09:53:16+00:00","author":{"@id":"https:\/\/www.septabene.si\/#\/schema\/person\/65ad2ca435785c4e4235f5a245adfc98"},"description":"Nova in\u00a0vitro \u0161tudija o pastilah s fiksno kombinacijo benzidamina in cetilpiridinijevega klorida je potrdila njihovo protivirusno delovanje proti SARS-CoV-2.","breadcrumb":{"@id":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#breadcrumb"},"inLanguage":"sl-SI","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.septabene.si\/koristno\/bolezni\/novi-dokazi-o-protivirusnem-delovanju-pastil-za-grlo\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Domov","item":"https:\/\/www.septabene.si\/"},{"@type":"ListItem","position":2,"name":"Koristno","item":"https:\/\/www.septabene.si\/koristno\/"},{"@type":"ListItem","position":3,"name":"Bolezni","item":"https:\/\/www.septabene.si\/koristno\/bolezni\/"},{"@type":"ListItem","position":4,"name":"Novi dokazi o protivirusnem delovanju pastil za grlo"}]},{"@type":"Person","@id":"https:\/\/www.septabene.si\/#\/schema\/person\/65ad2ca435785c4e4235f5a245adfc98","name":"doriscnj","image":{"@type":"ImageObject","@id":"https:\/\/www.septabene.si\/#personlogo","inLanguage":"sl-SI","url":"https:\/\/secure.gravatar.com\/avatar\/dc6aa88475708565cd14d855a73ba2b5?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/dc6aa88475708565cd14d855a73ba2b5?s=96&d=mm&r=g","caption":"doriscnj"},"url":"https:\/\/www.septabene.si\/author\/doriscnj\/"}]}},"_links":{"self":[{"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/posts\/1626"}],"collection":[{"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/comments?post=1626"}],"version-history":[{"count":11,"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/posts\/1626\/revisions"}],"predecessor-version":[{"id":1691,"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/posts\/1626\/revisions\/1691"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/media\/1602"}],"wp:attachment":[{"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/media?parent=1626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/categories?post=1626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.septabene.si\/wp-json\/wp\/v2\/tags?post=1626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}